1,870 research outputs found

    Atmospheric propagation effects on radio interferometry

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    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Earth, Atmospheric and Planetary Sciences, 1986.MICROFICHE COPY AVAILABLE IN ARCHIVES AND LINDGREN.Bibliography: leaves 278-284.by James Louis Davis.Ph.D

    Retrievals of thick cloud optical depth from the Geoscience Laser Altimeter System (GLAS) by calibration of solar background signal

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    Laser beams emitted from the Geoscience Laser Altimeter System (GLAS), as well as other spaceborne laser instruments, can only penetrate clouds to a limit of a few optical depths. As a result, only optical depths of thinner clouds (< about 3 for GLAS) are retrieved from the reflected lidar signal. This paper presents a comprehensive study of possible retrievals of optical depth of thick clouds using solar background light and treating GLAS as a solar radiometer. To do so one must first calibrate the reflected solar radiation received by the photon-counting detectors of the GLAS 532-nm channel, the primary channel for atmospheric products. Solar background radiation is regarded as a noise to be subtracted in the retrieval process of the lidar products. However, once calibrated, it becomes a signal that can be used in studying the properties of optically thick clouds. In this paper, three calibration methods are presented: (i) calibration with coincident airborne and GLAS observations, (ii) calibration with coincident Geostationary Opera- tional Environmental Satellite (GOES) and GLAS observations of deep convective clouds, and (iii) cali- bration from first principles using optical depth of thin water clouds over ocean retrieved by GLAS active remote sensing. Results from the three methods agree well with each other. Cloud optical depth (COD) is retrieved from the calibrated solar background signal using a one-channel retrieval. Comparison with COD retrieved from GOES during GLAS overpasses shows that the average difference between the two retriev- als is 24%. As an example, the COD values retrieved from GLAS solar background are illustrated for a marine stratocumulus cloud field that is too thick to be penetrated by the GLAS laser. Based on this study, optical depths for thick clouds will be provided as a supplementary product to the existing operational GLAS cloud products in future GLAS data releases

    A Principled Approach to GraphQL Query Cost Analysis

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    International audienceThe landscape of web APIs is evolving to meet new client requirements and to facilitate how providers fulfill them. A recent web API model is GraphQL, which is both a query language and a runtime. Using GraphQL, client queries express the data they want to retrieve or mutate, and servers respond with exactly those data or changes. GraphQL's expressiveness is risky for service providers because clients can succinctly request stupendous amounts of data, and responding to overly complex queries can be costly or disrupt service availability. Recent empirical work has shown that many service providers are at risk. Using traditional API management methods is not sufficient, and practitioners lack principled means of estimating and measuring the cost of the GraphQL queries they receive. In this work, we present a linear-time GraphQL query analysis that can measure the cost of a query without executing it. Our approach can be applied in a separate API management layer and used with arbitrary GraphQL backends. In contrast to existing static approaches, our analysis supports common GraphQL conventions that affect query cost, and our analysis is provably correct based on our formal specification of GraphQL semantics. We demonstrate the potential of our approach using a novel GraphQL query-response corpus for two commercial GraphQL APIs. Our query analysis consistently obtains upper cost bounds, tight enough relative to the true response sizes to be actionable for service providers. In contrast, existing static GraphQL query analyses exhibit over-estimates and under-estimates because they fail to support GraphQL conventions

    Traditional and Health-Related Philanthropy: The Role of Resources and Personality

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    I study the relationships of resources and personality characteristics to charitable giving, postmortem organ donation, and blood donation in a nationwide sample of persons in households in the Netherlands. I find that specific personality characteristics are related to specific types of giving: agreeableness to blood donation, empathic concern to charitable giving, and prosocial value orientation to postmortem organ donation. I find that giving has a consistently stronger relation to human and social capital than to personality. Human capital increases giving; social capital increases giving only when it is approved by others. Effects of prosocial personality characteristics decline at higher levels of these characteristics. Effects of empathic concern, helpfulness, and social value orientations on generosity are mediated by verbal proficiency and church attendance.

    Communications Biophysics

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    Contains research objectives and summary of research.National Institutes of Health (Grant 5 PO1 GM14940-07)National Institutes of Health (Grant 1 RO1 NS11000-01)Clarence J. LeBel FundNational Institutes of Health (Grant 1 RO1 NS10737-01)National Aeronautics and Space Administration (Grant NGL 22-009-304)Boston City Hospital Purchase Order 1176-21335B-D Electrodyne Division, Becton Dickinson and Company (Grant)Chicago Musical Instrument Company (Grant

    Institutional and Individual Factors Affecting Scientists\u27 Data-Sharing Behaviors: A Multilevel Analysis

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    The objective of this research was to investigate the institutional and individual factors that influence scientists\u27 data-sharing behaviors across different scientific disciplines. Two theoretical perspectives, institutional theory, and theory of planned behavior, were employed in developing a research model that showed the complementary nature of the institutional and individual factors influencing scientists\u27 data-sharing behaviors. This research used a survey method to examine to what extent those institutional and individual factors influence scientists\u27 data-sharing behaviors in a range of scientific disciplines. A national survey (with 1,317 scientists in 43 disciplines) showed that regulative pressure by journals, normative pressure at a discipline level, and perceived career benefit and scholarly altruism at an individual level had significant positive relationships with data-sharing behaviors, and that perceived effort had a significant negative relationship. Regulative pressure by funding agencies and the availability of data repositories at a discipline level and perceived career risk at an individual level were not found to have any significant relationships with data-sharing behaviors

    Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

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    Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts
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